ABOUT esKETAMINE
Esketamine (Spravato) is an insurance-covered medication, made from part of the ketamine molecule and is approved by the FDA for the treatment of treatment resistant major depressive disorder and major depressive disorder with acute suicidal ideation. It is delivered as a nasal spray for in-office treatment. This derivative of the ketamine molecule is isolated from the whole molecule because due to its potency, it can be used at lower doses.
Esketamine can be approved for coverage by insurance in those who have tried at least two other antidepressant medications and have not experienced symptom improvement by 50% or more, or those with severe depression with heightened suicide risk.
Spravato Treatment Timeline
Weeks 1-4
Twice Weekly
Weeks 5-8
Once Weekly
Weeks 9+
Once Weekly or Every Two Weeks
What to expect during spravato treatment?
STEP 1
Our team will prepare you for the day’s dose then show you how to self-administer the nasal spray.
STEP 2
Relax in our office treatment room for the two hours that the treatment is active.* Two hours ensures you return to your normal, clear sensorium so that you may continue on with your day.
*Spravato is not a take-home medication. It must be taken in-office, under the supervision of Hudson Mind’s clinical team.
Spravato vs. IV Ketamine Therapy
| Spravato | IV Ketamine Therapy | |
|---|---|---|
| Bioavailability | 25%-50% | 100% |
| FDA-Approval | Yes | No |
| Covered by Insurance | Yes | No |
| Medication Requirements | Spravato is taken in conjunction with an oral antidepressant. | None |