At Thrive Mind Psychiatry, we offer Esketamine treatment for individuals struggling with treatment-resistant depression who have not found relief through traditional medications. As an FDA-approved, insurance-covered option, esketamine (Spravato®) provides a new pathway toward stability, clarity, and emotional recovery.
A New Option for Treatment-Resistant Depression
Esketamine treatment offers an innovative solution for treatment-resistant depression, working through a different mechanism than traditional medications and often improving symptoms within hours to days rather than weeks. For those searching for esketamine treatment near me, Thrive Mind Psychiatry provides safe, structured, in-office treatment guided by experienced clinicians.
What Is Esketamine (Spravato®) and How Does It Work?
Esketamine (Spravato®) is a nasal spray medication derived from one component of the ketamine molecule. Its unique structure allows it to work at lower doses while providing powerful and rapid antidepressant effects. Delivered in-office under medical supervision, esketamine helps restore disrupted neural connections in the brain, targeting pathways involved in mood, emotional regulation, and cognitive functioning.
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This makes it especially effective for people with treatment-resistant depression, including those with acute suicidal ideation. Because it is FDA-approved, esketamine treatment for depression is often covered by insurance when individuals have tried at least two antidepressants without meaningful improvement.
What to expect during Spravato treatment?
STEP 1
Our team will prepare you for the day’s dose, then show you how to self-administer the nasal spray.
STEP 2
Relax in our office treatment room for the two hours that the treatment is active.
*Two hours ensures you return to your normal, clear sensorium so that you may continue on with your day.
*Spravato is not a take-home medication. It must be taken in-office, under the supervision of Hudson Mind’s clinical team.
Spravato vs. IV Ketamine Therapy
If you're considering esketamine treatment and want expert guidance, our team is here to help you understand your options and build a plan that aligns with your goals and needs.
Spravato |
IV Ketamine Therapy |
|
|---|---|---|
| Bioavailability | 25%-50% | 100% |
| FDA-Approval | Yes | No |
| Covered by Insurance | Yes | No |
| Medication Requirements | Spravato is taken in conjunction with an oral antidepressant. | None |
Frequently Asked Questions
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Esketamine is administered as a nasal spray in a calm, private treatment room. After dosing, you’ll rest comfortably while the medication takes effect, and a clinician will monitor you throughout the session.
Most appointments last about two hours, and patients typically attend treatment twice weekly at the beginning before gradually tapering as symptoms improve.
Temporary esketamine effects may include mild dissociation, dizziness, or drowsiness — all of which fade within the observation period. You’ll need someone to drive you home after each visit.
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Esketamine may be a strong option if:
You’ve tried at least two antidepressant medications without significant improvement
You are experiencing treatment-resistant depression
You have severe depression with increased suicidal thoughts
You prefer a medication with a rapid onset of action
You are searching for a trusted esketamine treatment center in NYC
A consultation helps determine whether Spravato® is the best next step in your treatment plan.